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In preclinical models, it is studied for how it interacts with the inner mitochondrial environment—particularly in research themes involving cardiolipin (a key lipid in the inner mitochondrial membrane), respiratory chain organization, and experimental readouts related to energy production and oxidative stress

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Gut microbiome dysbiosis, marked by a loss of microbial diversity and an increase in pro-inflammatory species, significantly disrupts the delicate balance of metabolites that are crucial for maintaining cardiovascular health [54]