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The approach is also compatible with the controlled production in stirred tank bioreactors as recently demonstrated for cardiac and hematopoietic lineages 77,78 and will provide the field with a potentially game-changing resource to allow the development of clinical as well as screening platforms where the requirement will be in the millions of organoids rather than today’s laboratory scale

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28 Moreover, a biomechanical study using discomanometry has shown that not only the discs adjacent to complete vertebral burst fractures but also the non-adjacent discs at the next lower segments were injured