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These neuropathic symptoms from oxaliplatin arise from direct interaction with voltage-gated sodium channels leading to altered nerve excitability.26–28 More generally, the platinum-based compounds are thought to cause neuropathy by binding to nuclear and mitochondrial DNA, leading to apoptosis

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“Borate compounds, like borax, have been used in cosmetics as preservatives, emulsifiers, and pH adjusters,” Kline said via email